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The MTHFR polymorphisms within the homozygous or compound heterozygous sort only cut down enzyme output mildly and are So of restricted pathogenicity.12 The 677C>T polymorphism inside the homozygous kind could lead to mild homocystinuria due to lessened MTHFR exercise.As we age, gradual DNA hypomethylation occurs (expanding the need for methyl team